Is there any relationship between hematologic parameters and presbyacusis in geriatric patients ?
Submitted on May 28, 2019
Biochemistry (medical) Geriatrics and Gerontology Otorhinolaryngology
Now published in Journal of Clinical Medicine of Kazakhstan doi: 10.23950/1812-2892-JCMK-00688
Abstract
ABSTRACT Objectives: Presbycusis is the most common sensory deficit in the aging population. Blood examinations are inexpensive and simple methods for analyzing red cells, white cells and platelets for coagulation, inflammation, thrombosis. In the present study, we aimed to investigate the relationship between presbycusis and inflammatory and prothrombotic factors that can be measured routinely in complete blood count (CBC) tests with little cost in addition with hearing loss types . Materials and Methods: The study was conducted prospectively .Group I comprised patients with presbycusis aged ≥65 years (n=31), group 2 was constituted by healthy volunteers aged ≥65 years (n=30). Audiograms were categorized according to hearing levels at 0.5, 1, 2, 4, and 8 kHz: high-frequency steeply sloping (HFSS), flat configuration, high-frequency gently sloping (HFGS). Complete blood counts including hemoglobin(Hb), RDW(red cell distribution width), WBC(white blood cell), neutrophil-to-lymphocyte ratio (NLR) , platelets(PLT), platelet-to- lymphocyte ratio (PLR) ,PCT( procalcitonin), PDW (platelet distribution width), MPV (mean platelet volume), and fibrinogen were analyzed. Results: There were no significant differences between the patient and control groups in terms of Hb, RDW, WBC, NLR, PLT, PCT, PDW, MPV, PLR and fibrinogen(p>0.05). There were no significant differences between the FLAT, HFSS and normal groups in terms of mean Hb, RDW, WBC, NLR, PLT, PCT, PDW, MPV, PLR and fibrinogen(p>0.05) . Conclusion: No difference was detected in terms of the presbyacusis ,hearing loss types and CBC parameters. According to the study results presbyacusis types and inflammatory mediators did not correlate with each other. Key-words: Presbycusis, geriatric , complete blood count, inflammatory markers, hearing loss
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